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Article

Does the MTHFR 677C-->T variant affect the Recommended Dietary Allowance for folate in the US population?

The American journal of clinical nutrition - 1 Apr 2009

Robitaille Julie, Hamner Heather C, Cogswell Mary E, Yang Quanhe

Abstract excerpt

BACKGROUND: The MTHFR 677C-->T variant is associated with reduced enzyme activity, abnormalities of folate metabolism, and potential increase in folate requirement. The effect of this variant on the Recommended Dietary Allowance (RDA) for folate is unclear. OBJECTIVE: The aim of this study was to assess the effect of the MTHFR 677C-->T polymorphism on the current folate RDA for US adults aged > or =19 y (400...

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Source

Identifiers

PMID: 19225123
DOI: 10.3945/ajcn.2008.27282

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Does the MTHFR 677C-->T variant affect the Recommended Dietary Allowance for folate in the US population?PMID 19225123Read ↗

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