Article
Blood-tissue analysis of TP53 polymorphisms and survival of patients with glioma.
Journal of neurosurgical sciences - 1 Feb 2021
Panciani Pier Paolo, Giordana Maria T, Gallone Salvatore, Muratori Andrea, Rotunno Rosaria, Migliorati Karol, Spena Giannantonio, Ducati Alessandro, Fontanella Marco
Abstract excerpt
BACKGROUND: The role of single nucleotide polymorphisms (SNPs) in TP53 in the pathogenesis of glioma is still debated. The aim of our study was to investigate the role of several TP53 SNPs in the risk of glioma and their possible role as prognostic biomarkers of overall and progression-free survival. METHODS: We examined 12 SNPs in TP53 from peripheral blood and neoplastic tissue of patients with a diagnosis of...
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