Article
Spatial distribution of G6PD deficiency variants across malaria-endemic regions.
Malaria journal - 15 Nov 2013
Howes Rosalind E, Dewi Mewahyu, Piel Frédéric B, Monteiro Wuelton M, Battle Katherine E, Messina Jane P, Sakuntabhai Anavaj, Satyagraha Ari W, Williams Thomas N, Baird J Kevin, Hay Simon I
Abstract excerpt
BACKGROUND: Primaquine is essential for malaria control and elimination since it is the only available drug preventing multiple clinical attacks by relapses of Plasmodium vivax. It is also the only therapy against the sexual stages of Plasmodium falciparum infectious to mosquitoes, and is thus useful in preventing malaria transmission. However, the difficulties of diagnosing glucose-6-phosphate dehydrogenase...
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