Article
Glucose-6-Phosphate Dehydrogenase Deficiency Genetic Variants in Malaria Patients in Southwestern Ethiopia.
The American journal of tropical medicine and hygiene - 1 Jan 2018
Carter Tamar E, Mekonnen Seleshi Kebede, Lopez Karen, Bonnell Victoria, Damodaran Lambodhar, Aseffa Abraham, Janies Daniel A
Abstract excerpt
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked erythrocyte enzyme disorder with relevance to malaria treatment policy. Treatment with the antimalarial primaquine can result in hemolytic anemia in G6PD-deficient patients. With increased interest in primaquine use, it is important to identify G6PD variants in Ethiopia to inform malaria treatment policy. In the present study, mutations in the...
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