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Genetic variants of antioxidant and xenobiotic metabolizing enzymes and their association with prostate cancer: A meta-analysis and functional in silico analysis.

The Science of the total environment - 10 Nov 2023

Álvarez-González Beatriz, Porras-Quesada Patricia, Arenas-Rodríguez Verónica, Tamayo-Gómez Alba, Vázquez-Alonso Fernando, Martínez-González Luis Javier, Hernández Antonio F, Álvarez-Cubero María Jesús

Abstract excerpt

The development and progression of prostate cancer (PCa) depends on complex interactions between genetic, environmental and dietary factors that modulate the carcinogenesis process. Interactions between chemical exposures and genetic polymorphisms in genes encoding xenobiotic metabolizing enzymes (XME), antioxidant enzymes and DNA repair enzymes have been reported as the main drivers of cancer. Thus, a better...

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PMID: 37453710
DOI: 10.1016/j.scitotenv.2023.165530

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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