Article
Mutational specificity of ethyl methanesulfonate in excision-repair-proficient and -deficient strains of Drosophila melanogaster.
Molecular & general genetics : MGG - 1 Oct 1991
Pastink A, Heemskerk E, Nivard M J, van Vliet C J, Vogel E W
Abstract excerpt
The vermilion gene was used as a target to determine the mutational specificity of ethyl methanesulfonate (EMS) in germ cells of Drosophila melanogaster. To study the impact of DNA repair on the type of mutations induced, both excision-repair-proficient (exr+) and excision-repair-deficient (exr-) strains were used for the isolation of mutant flies. In all, 28 mutants from the exr+ strain and 24 from the exr-...
Topics
- Animals
- Base Sequence
- DNA Repair
- Drosophila melanogaster
- Ethyl Methanesulfonate
- Molecular Sequence Data
- Mutation