Article
Mutation spectra of 1,2-dibromoethane, 1,2-dichloroethane and 1-bromo-2-chloroethane in excision repair proficient and repair deficient strains of Drosophila melanogaster.
Carcinogenesis - 1 May 1994
Ballering L A, Nivard M J, Vogel E W
Abstract excerpt
DNA sequence changes produced by 1,2-dibromoethane (DBE), 1,2-dichloroethane (DCE) and 1-bromo-2-chloroethane (BCE) were analyzed using the vermilion locus of Drosophila melanogaster. Under excision repair proficient (exr+) conditions (mutagenized exr+ males mated with exr+ females) all mutants i...
Topics
- Animals
- Base Sequence
- DNA Damage
- DNA Repair
- Drosophila melanogaster
- Ethane
- Ethylene Dibromide
- Ethylene Dichlorides
- Female
- Gene Deletion
- Hydrocarbons, Halogenated
- Male
- Molecular Sequence Data
- Mutation
- Spermatids
- Spermatozoa