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Article

A polymorphism in the promoter region of Ku70/XRCC6, associated with breast cancer risk and oestrogen exposure.

Journal of cancer research and clinical oncology - 1 Sept 2009

Willems Petra, De Ruyck Kim, Van den Broecke Rudy, Makar Amin, Perletti Gianpaolo, Thierens Hubert, Vral Anne

Abstract excerpt

PURPOSE: Polymorphisms in double strand break repair genes could be involved in genetic breast cancer predisposition as enhanced chromosomal radiosensitivity is a hallmark for breast cancer. Previously, the c.-1310 C>G SNP, located in the Ku70 promoter, showed a significant odds ratio (OR) of 1.8...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19219618
DOI: 10.1007/s00432-009-0556-x

Genes

XRCC6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19219618-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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