The Ku70 -1310C/G promoter polymorphism is associated with breast cancer susceptibility in Chinese Han population.

doi:10.1007/s11033-011-0773-7

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The Ku70 -1310C/G promoter polymorphism is associated with breast cancer susceptibility in Chinese Han population.

Molecular biology reports - 1 Jan 2012

He Wenshan, Luo Sijia, Huang Tao, Ren Jinghua, Wu Xiaoling, Shao Jun, Zhu Qingyao

Abstract excerpt

Ku70 plays an important role in the DSBR (DNA double-strand breaks repair) and maintenance of genomic integrity. Genetic variations within human Ku70 have been demonstrated to be associated with increased risk of several types of cancers. In this hospital-based case-control study, we aimed to investigate whether a single nucleotide polymorphism (SNP) in the promoter region (rs2267437) of Ku70 gene is associated...

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PMID: 21556760
DOI: 10.1007/s11033-011-0773-7

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