Article
Oral cancer and genetic polymorphism of DNA double strand break gene Ku70 in Taiwan.
Oral oncology - 1 Nov 2008
Bau Da-Tian, Tseng Hsien-Chang, Wang Chung-Hsing, Chiu Chang-Fang, Hua Chun-Hung, Wu Cheng-Nan, Liang Shiu-Yun, Wang Cheng-Li, Tsai Chia-Wen, Tsai Ming-Hsui
Abstract excerpt
The DNA repair gene Ku70, an important caretaker of the overall genome stability, is thought to play a major role in the DNA double strand break repair system. It is known that defects in double strand break repair capacity can lead to irreversible genomic instability. However, the polymorphic variants of Ku70 and their association with oral cancer susceptibility has never been reported on. In this hospital-based...
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