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Article

Association between polymorphisms at promoters of XRCC5 and XRCC6 genes and risk of breast cancer.

Medical oncology (Northwood, London, England) - 1 Apr 2014

Rajaei Mehrdad, Saadat Iraj, Omidvari Shahpour, Saadat Mostafa

Abstract excerpt

Variation in DNA repair genes is one of the mechanisms that may lead to variation in DNA repair capacity. Ku, a heterodimeric DNA-binding complex, is directly involved in repair of DNA double-strand breaks. Ku consists of two subunits, Ku70 and Ku80, which are encoded by the XRCC6 and XRCC5 genes, respectively. In the present study, we investigated whether common genetic variant in variable number of tandem...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24615008
DOI: 10.1007/s12032-014-0885-8

Genes

XRCC5
XRCC6

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