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Article

Genetic variation in DNA repair gene XRCC7 (G6721T) and susceptibility to breast cancer.

Gene - 15 Aug 2012

Nasiri Meysam, Saadat Iraj, Omidvari Shahpour, Saadat Mostafa

Abstract excerpt

The human XRCC7 is a DNA double-strand break (DSBs) repair gene, involved in non-homologous end joining (NHEJ). It is speculated that DNA DSBs repair have an important role during development of breast cancer. The human XRCC7 is a NHEJ DSBs repair gene. Genetic variation G6721T of XRCC7 (rs7003908) is located in the intron 8 of the gene. This polymorphism may regulate splicing and cause mRNA instability. In the...

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Identifiers

PMID: 22634101
DOI: 10.1016/j.gene.2012.04.065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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