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Article

RAS gene mutations in multiple myeloma and related monoclonal gammopathies.

The Kobe journal of medical sciences - 1 Feb 1991

Matozaki S, Nakagawa T, Nakao Y, Fujita T

Abstract excerpt

The presence of RAS gene mutations in precancerous lesions suggests that they participate in the early stages of neoplastic development. Furthermore, neoplastic progression from monoclonal gammopathy of undetermined significance (MGUS) to overt multiple myeloma (MM) have been frequently observed....

Topics

Base Sequence
Codon
Genes, ras
Humans
Molecular Sequence Data
Multiple Myeloma
Mutation
Nucleic Acid Hybridization
Oligonucleotide Probes
Paraproteinemias
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1921261

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1921261-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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RAS gene mutations in multiple myeloma and related monoclonal gammopathies.PMID 1921261Read ↗

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Clinical and biological significance of RAS mutations in multiple myelomaSemantic proximity Read ↗

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Possible roles for activating RAS mutations in the MGUS to MM transition and in the intramedullary to extramedullary transition in some plasma cell tumors.Semantic proximity Read ↗

Activating mutations of N- and K-ras in multiple myeloma show different clinical associations: analysis of the Eastern Cooperative Oncology Group Phase III TrialSemantic proximity Read ↗

Oncogenes in multiple myeloma: point mutation of N-ras.Semantic proximity Read ↗

High incidence of N and K-Ras activating mutations in multiple myeloma and primary plasma cell leukemia at diagnosis.Semantic proximity Read ↗

Detection of N-Ras codon 61 mutations in subpopulations of tumor cells in multiple myeloma at presentation.Semantic proximity Read ↗

N-ras and p53 gene mutations are very rare events in multiple myeloma.Semantic proximity Read ↗

Pathogenetic relation between monoclonal gammopathies of undetermined significance and multiple myeloma.Semantic proximity Read ↗

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