Mutational activation of N- and K-ras oncogenes in plasma cell dyscrasias.

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Article

Mutational activation of N- and K-ras oncogenes in plasma cell dyscrasias.

Blood - 15 May 1993

Corradini P, Ladetto M, Voena C, Palumbo A, Inghirami G, Knowles D M, Boccadoro M, Pileri A

Abstract excerpt

The frequency of N- and K-ras oncogene mutations was investigated in plasma cell dyscrasias. Genomic DNAs from 128 patients were selected for this study: 30 monoclonal gammopathies of undetermined significance, 8 solitary plasmacytomas, 77 multiple myelomas (MM), and 13 plasma cell leukemias (PCL...

Topics

Base Sequence
Bone Marrow
Codon
DNA, Neoplasm
Gene Expression Regulation, Neoplastic
Genes, ras
Humans
Immunoglobulins
Leukemia, Plasma Cell
Molecular Sequence Data
Multiple Myeloma
Mutation
Neoplasm Staging
Oligodeoxyribonucleotides
Paraproteinemias
Plasmacytoma
Point Mutation
Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 8490179

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8490179-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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