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Article

Pathogenetic relation between monoclonal gammopathies of undetermined significance and multiple myeloma.

Stem cells (Dayton, Ohio) - 1 Aug 1995

Greipp P R, Lust J A

Abstract excerpt

Plasma cell atypia and cell proliferation changes which occur during the progression from monoclonal gammopathy of undetermined significance (MGUS) to multiple myeloma (MM) are accompanied by critical changes in neoplastic plasma cells and marrow stromal cells. Key elements include paracrine secretion of interleukin 6 (IL-6) by marrow stromal cells resulting from interleukin 1 beta (IL-1 beta) secreted by myeloma...

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PMID: 8520496

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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