Article
Pathogenetic relation between monoclonal gammopathies of undetermined significance and multiple myeloma.
Stem cells (Dayton, Ohio) - 1 Aug 1995
Greipp P R, Lust J A
Abstract excerpt
Plasma cell atypia and cell proliferation changes which occur during the progression from monoclonal gammopathy of undetermined significance (MGUS) to multiple myeloma (MM) are accompanied by critical changes in neoplastic plasma cells and marrow stromal cells. Key elements include paracrine secr...
Topics
- Biomarkers
- Cell Division
- Cytokines
- Genes, Tumor Suppressor
- Humans
- Multiple Myeloma
- Neoplastic Stem Cells
- Oncogenes
- Paraproteinemias
- Phenotype
- Plasma Cells
- T-Lymphocytes