RAS mutations are uncommon in multiple myeloma and other monoclonal gammopathies.

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Article

RAS mutations are uncommon in multiple myeloma and other monoclonal gammopathies.

International journal of oncology - 1 Oct 2005

Martín Paloma, Santón Almudena, García-Cosío Mónica, Bellas Carmen

Abstract excerpt

Monoclonal gammopathies are a group of diseases characterised by the proliferation of a single clone of plasma cells that produce a homogeneous monoclonal protein (M protein or myeloma protein) that consist of two heavy polypeptide chains of the same class and subclass and two light polypeptide chains of the same type. Multiple myeloma (MM) and monoclonal gammopathy of undetermined significance (MGUS) are the...

Topics

Alleles
Bone Marrow
Bone Marrow Cells
Codon
DNA Primers
Female
Gene Expression Regulation, Neoplastic
Genes, ras
Humans
Membrane Glycoproteins
Multiple Myeloma
Mutation
Myeloma Proteins
Paraproteinemias
Peptides
Point Mutation
Polymerase Chain Reaction
Proteoglycans

Source

Open in PubMed

Identifiers

PMID: 16142319

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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