Article
Genetic variation in the ADIPOR2 gene is associated with liver fat content and its surrogate markers in three independent cohorts.
European journal of endocrinology - 1 Apr 2009
Kotronen Anna, Yki-Järvinen Hannele, Aminoff Anna, Bergholm Robert, Pietiläinen Kirsi H, Westerbacka Jukka, Talmud Philippa J, Humphries Steve E, Hamsten Anders, Isomaa Bo, Groop Leif, Orho-Melander Marju, Ehrenborg Ewa, Fisher Rachel M
Abstract excerpt
AIMS: We investigated whether polymorphisms in candidate genes involved in lipid metabolism and type 2 diabetes are related to liver fat content. METHODS: Liver fat content was measured using proton magnetic resonance spectroscopy ((1)H-MRS) in 302 Finns, in whom single nucleotide polymorphisms (SNPs) in acyl-CoA synthetase long-chain family member 4 (ACSL4), adiponectin receptors 1 and 2 (ADIPOR1 and ADIPOR2),...
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