Article
The rs11187533 C>T Variant of the FFAR4 Gene Is Associated with Lower Levels of Fasting Glucose and Decreases in Markers of Liver Injury in Children with Obesity.
Annals of nutrition & metabolism - 1 Jan 2020
Codoñer-Alejos Alan, Carrasco-Luna Joaquín, Codoñer-Franch Pilar
Abstract excerpt
INTRODUCTION: Genetic factors can modulate the development of associated comorbidities in obesity. It has been shown that loss-of-function variants of the free fatty acid receptor 4 (FFAR4) gene negatively affect obesity comorbidities such as insulin resistance and fatty liver disease. OBJECTIVE: To test the relationships of metabolic factors in children with obesity with variants of the FFAR4 gene. METHODS: We...
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