Article
Genetic variants of adiponectin receptor 2 are associated with increased adiponectin levels and decreased triglyceride/VLDL levels in patients with metabolic syndrome.
Cardiovascular diabetology - 15 May 2006
Broedl Uli C, Lehrke Michael, Fleischer-Brielmaier Elisabeth, Tietz Anne B, Nagel Jutta M, Göke Burkhard, Lohse Peter, Parhofer Klaus G
Abstract excerpt
BACKGROUND: Adiponectin acts as an antidiabetic, antiinflammatory and antiatherogenic adipokine. These effects are assumed to be mediated by the recently discovered adiponectin receptors AdipoR1 and AdipoR2. AIM: The purpose of this study was to determine whether variations in the AdipoR1 and AdipoR2 genes may contribute to insulin resistance, dyslipidemia and inflammation. METHODS: We sequenced all seven coding...
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