Article
Association between variants in the genes for adiponectin and its receptors with insulin resistance syndrome (IRS)-related phenotypes in Mexican Americans.
Diabetologia - 1 Oct 2006
Richardson D K, Schneider J, Fourcaudot M J, Rodriguez L M, Arya R, Dyer T D, Almasy L, Blangero J, Stern M P, Defronzo R A, Duggirala R, Jenkinson C P
Abstract excerpt
AIMS/HYPOTHESIS: The aim of this study was to examine whether genetic variation in ADIPOQ, ADIPOR1 and ADIPOR2 may contribute to increased susceptibility to components of the insulin resistance syndrome (IRS). MATERIALS AND METHODS: We genotyped single-nucleotide polymorphisms (SNPs) in ADIPOQ, ADIPOR1 and ADIPOR2 in Mexican American subjects (N=439) and performed an association analysis of IRS-related traits....
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