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Article

The core trisaccharide of an N-linked glycoprotein intrinsically accelerates folding and enhances stability.

Proceedings of the National Academy of Sciences of the United States of America - 3 Mar 2009

Hanson Sarah R, Culyba Elizabeth K, Hsu Tsui-Ling, Wong Chi-Huey, Kelly Jeffery W, Powers Evan T

Abstract excerpt

The folding energetics of the mono-N-glycosylated adhesion domain of the human immune cell receptor cluster of differentiation 2 (hCD2ad) were studied systematically to understand the influence of the N-glycan on the folding energy landscape. Fully elaborated N-glycan structures accelerate foldin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19204290
DOI: 10.1073/pnas.0810318105
PMCID: PMC2651298

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19204290-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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