How and why plants and human N-glycans are different: Insight from molecular dynamics into the “glycoblocks” architecture of complex carbohydrates

Abstract excerpt

N-glycosylation is one of the most abundant and diverse post-translational modifications of proteins, implicated in protein folding and structural stability, and mediating interactions with receptors and with the environment. All N-glycans share a common core from which linear or branched arms stem from, with functionalization specific to different species and to the cells’ health and disease state. This diversity...

Topics

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• Carbohydrate Chemistry and Synthesis
• Glycosylation and Glycoproteins Research
• Influenza Virus Research Studies
• Monoclonal and Polyclonal Antibodies Research
• Mosquito-borne diseases and control
• Vector-borne infectious diseases
• Viral Infections and Outbreaks Research
• Virology and Viral Diseases

Identifiers and source

Literature Corpus work

f00a49da-b153-5792-a8db-cd24cade461b

DOI

10.1101/2020.05.22.110528