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Article

Tissue-specific roles of ABCA1 influence susceptibility to atherosclerosis.

Arteriosclerosis, thrombosis, and vascular biology - 1 Apr 2009

Brunham Liam R, Singaraja Roshni R, Duong MyNgan, Timmins Jenelle M, Fievet Catherine, Bissada Nagat, Kang Martin H, Samra Amrit, Fruchart Jean-Charles, McManus Bruce, Staels Bart, Parks John S, Hayden Michael R

Abstract excerpt

OBJECTIVE: The ATP-binding cassette transporter, subfamily A, member 1 (ABCA1) plays a key role in HDL cholesterol metabolism. However, the role of ABCA1 in modulating susceptibility to atherosclerosis is controversial. METHODS AND RESULTS: We investigated the role of ABCA1 in atherosclerosis usi...

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Topics

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Share to ATP Binding Cassette Transporter 1
Share to Cholesterol, HDL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholesterol, LDL

Share to Cholesterol, VLDL

Share to Chromosomes, Artificial, Bacterial

Share to Dietary Fats

Share to Macrophages, Peritoneal

Share to Receptors, LDL

Source

Identifiers

PMID: 19201688
DOI: 10.1161/ATVBAHA.108.182303

Genes

ABCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19201688-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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