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Article

Independent protective roles for macrophage Abcg1 and Apoe in the atherosclerotic lesion development.

Atherosclerosis - 1 Aug 2009

Lammers Bart, Out Ruud, Hildebrand Reeni B, Quinn Carmel M, Williamson David, Hoekstra Menno, Meurs Illiana, Van Berkel Theo J C, Jessup Wendy, Van Eck Miranda

Abstract excerpt

OBJECTIVE: ATP-binding cassette transporter G1 (Abcg1) and apolipoprotein E (Apoe) play a role in macrophage cholesterol efflux and consequently the development of atherosclerosis. A possible interaction between Abcg1 and Apoe in cholesterol efflux was postulated, but the potential combined action of these proteins on atherosclerotic lesion formation is unclear. METHODS: LDL receptor knockout (KO) mice were...

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Identifiers

PMID: 19217108
DOI: 10.1016/j.atherosclerosis.2009.01.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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