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Article

Differential expression of immunophilins FKBP51 and FKBP52 in the frontal cortex of HIV-infected patients with major depressive disorder.

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology - 1 Jun 2009

Tatro Erick T, Everall Ian P, Masliah Eliezer, Hult Britta J, Lucero Ginger, Chana Gursharan, Soontornniyomkij Virawudh, Achim Cristian L

Abstract excerpt

Patients infected with human immunodeficiency virus (HIV) have a higher risk of developing major depressive disorder (MDD) than the general population. Immunophilins FKBP51 and FKBP52 are expressed in cortical neurons and regulate the function of the glucocorticoid receptor (GR). Previous reports...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 19199039
DOI: 10.1007/s11481-009-9146-6
PMCID: PMC2929573

Genes

FKBP5
FKBP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19199039-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Differential expression of immunophilins FKBP51 and FKBP52 in the frontal cortex of HIV-infected patients with major depressive disorder.PMID 19199039Read ↗

Correlation of major depressive disorder symptoms with FKBP5 but not FKBP4 expression in human immunodeficiency virus-infected individuals.Semantic proximity Read ↗

FKBP51 levels negatively correlate with Depressive symptoms in Chronic Hepatitis CSemantic proximity Read ↗

The Role of FKBP5 in Mood Disorders: Action of FKBP5 on Steroid Hormone Receptors Leads to Questions About its Evolutionary ImportanceSemantic proximity Read ↗

FKBP5 genetic variation: association with selective serotonin reuptake inhibitor treatment outcomes in major depressive disorder.Semantic proximity Read ↗

Regulation of the glucocorticoid response to stress‐related disorders by the Hsp90‐binding immunophilin FKBP51Semantic proximity Read ↗

FKBP5 polymorphism is associated with major depression but not with bipolar disorder.Semantic proximity Read ↗

Role of FKBP5 and its genetic mutations in stress-induced psychiatric disorders: an opportunity for drug discoverySemantic proximity Read ↗

DNA sequence variants of the FKBP5 gene are associated with unipolar depression.Semantic proximity Read ↗

Genetic variation in FKBP5 associated with the extent of stress hormone dysregulation in major depression.Semantic proximity Read ↗

Modulation of glucocorticoid receptor nuclear translocation in neurons by immunophilins FKBP51 and FKBP52: Implications for major depressive disorderSemantic proximity Read ↗

Role of allelic variants of FK506-binding protein 51 (FKBP5) gene in the development of anxiety disorders.Semantic proximity Read ↗

Differential Dynamics and Roles of FKBP51 Isoforms and Their Implications for Targeted TherapiesSemantic proximity Read ↗

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