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Article

Correlation of major depressive disorder symptoms with FKBP5 but not FKBP4 expression in human immunodeficiency virus-infected individuals.

Journal of neurovirology - 1 Oct 2010

Tatro Erick T, Nguyen Timothy B, Bousman Chad A, Masliah Eliezer, Grant Igor, Atkinson J Hampton, Everall Ian P

Abstract excerpt

Major depressive disorder (MDD) is a significant cause of morbidity in people living with the human immunodeficiency virus (HIV). FKBP5 is a candidate gene with single-nucleotide polymorphisms (SNPs) rs1360780 and rs3800373 associated with MDD. This gene product and its relative, FKBP4, physically associate with the glucocorticoid receptor whose function is implicated in MDD pathophysiology. Because these genes...

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Source

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Identifiers

PMID: 20726698
DOI: 10.3109/13550284.2010.504248
PMCID: PMC3274491

Genes

FKBP5
FKBP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Correlation of major depressive disorder symptoms with FKBP5 but not FKBP4 expression in human immunodeficiency virus-infected individuals.PMID 20726698Read ↗

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