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Article

Rhb1 regulates the expression of secreted aspartic protease 2 through the TOR signaling pathway in Candida albicans.

Eukaryotic cell - 1 Feb 2012

Chen Yu-Ting, Lin Chia-Ying, Tsai Pei-Wen, Yang Cheng-Yao, Hsieh Wen-Ping, Lan Chung-Yu

Abstract excerpt

Candida albicans is a major fungal pathogen in humans. In C. albicans, secreted aspartyl protease 2 (Sap2) is the most highly expressed secreted aspartic protease in vitro and is a virulence factor. Recent research links the small GTPase Rhb1 to C. albicans target of rapamycin (TOR) signaling in response to nitrogen availability. The results of this study show that Rhb1 is related to cell growth through the...

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Identifiers

PMID: 22194462
DOI: 10.1128/EC.05200-11
PMCID: PMC3272892

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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