Article
Refining abacavir hypersensitivity diagnoses using a structured clinical assessment and genetic testing in the Swiss HIV Cohort Study.
Antiviral therapy - 1 Jan 2008
Rauch Andri, Nolan David, Thurnheer Christine, Fux Christoph A, Cavassini Matthias, Chave Jean-Philippe, Opravil Milos, Phillips Elizabeth, Mallal Simon, Furrer Hansjakob
Abstract excerpt
BACKGROUND: We aimed to assess the value of a structured clinical assessment and genetic testing for refining the diagnosis of abacavir hypersensitivity reactions (ABC-HSRs) in a routine clinical setting. METHODS: We performed a diagnostic reassessment using a structured patient chart review in individuals who had stopped ABC because of suspected HSR. Two HIV physicians blinded to the human leukocyte antigen...
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