The HCP5 single-nucleotide polymorphism: a simple screening tool for prediction of hypersensitivity reaction to abacavir.

doi:10.1086/591184

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Article

The HCP5 single-nucleotide polymorphism: a simple screening tool for prediction of hypersensitivity reaction to abacavir.

The Journal of infectious diseases - 15 Sept 2008

Colombo Sara, Rauch Andri, Rotger Margalida, Fellay Jacques, Martinez Raquel, Fux Christoph, Thurnheer Christine, Günthard Huldrych F, Goldstein David B, Furrer Hansjakob, Telenti Amalio

Abstract excerpt

The HLA-B 5701 allele is predictive of hypersensitivity reaction to abacavir, a response herein termed "ABC-HSR." This study of 1,103 individuals infected with human immunodeficiency virus assessed the usefulness of genotyping a HCP5 single-nucleotide polymorphism (SNP), rs2395029, in relation to...

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PMID: 18684101
DOI: 10.1086/591184

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18684101-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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