Article
Association study of CREB1 with Major Depressive Disorder and related phenotypes.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2009
Hettema John M, An Seon-Sook, van den Oord Edwin J C G, Neale Michael C, Kendler Kenneth S, Chen Xiangning
Abstract excerpt
Cyclic AMP response element binding protein (CREB) has been implicated in behavioral models of anxiety and depression, antidepressant response in humans, and suicide. One group reported a female-specific association of the CREB1 gene in early-onset Major Depressive Disorder (MDD), while another found no evidence of association with this phenotype. In this study, we sought to examine the evidence for association...
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