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Association study between variants in the fibrinogen gene cluster, fibrinogen levels and hypertension: results from the MONICA/KORA study.

Thrombosis and haemostasis - 1 Feb 2009

Kolz Melanie, Baumert Jens, Gohlke Henning, Grallert Harald, Döring Angela, Peters Annette, Wichmann H-Erich, Koenig Wolfgang, Illig Thomas

Abstract excerpt

Previous studies reported a gender-specific association between plasma fibrinogen concentrations and incident hypertension. We systematically analysed polymorphisms and haplotypes across the fibrinogen gene cluster with fibrinogen levels and assessed their contribution to prevalent hypertension in 2,200 men and 2,159 women from the population-based MONICA/KORA Augsburg study. Eleven tagging single nucleotide...

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Identifiers

PMID: 19190816

Genes

FGA
FGB
FGG

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