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Chromosomal Alterations during Lymphatic and Liver Metastasis Formation of Colorectal Cancer

1 Jan 2004

Abstract excerpt

Comparative genomic hybridization (CGH) was used to screen colorectal carcinomas for chromosomal aberrations that are associated with metastatic phenotype. In total, 63 tumor specimens from 40 patients were investigated, comprising 30 primary tumors, 22 systemic metastases (12 liver, 6 brain, and 4 abdominal wall metastases) and 11 lymph node tumors. Using statistical analysis and histograms to evaluate the...

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PMID: 15068668
DOI: 10.1016/s1476-5586(04)80050-2

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