Genetic changes and clonality relationship between primary colorectal cancers and their pulmonary metastases?An analysis by comparative genomic hybridization

Abstract excerpt

About 10% of colorectal carcinoma patients develop pulmonary metastases during their lifetime. We address whether and how the chromosomal abnormalities differ between the primary cancers and their metastatic counterparts, what the clonality relationship (CR) is between them, and whether certain genomic aberrations contribute to this disease progression. Comparative genomic hybridization (CGH) experiments were...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cholangiocarcinoma and Gallbladder Cancer Studies
• Share to Genetic factors in colorectal cancer
• Share to Genomic variations and chromosomal abnormalities