Article
Crosstalk between chromatin structure, nuclear compartmentalization, and telomere biology.
Cytogenetic and genome research - 1 Jan 2008
Gonzalez-Suarez I, Gonzalo S
Abstract excerpt
Telomeres are heterochromatic structures essential for the maintenance of genomic stability and the proliferative potential of human somatic cells. A minimal length of telomeric DNA repeats and proper binding of specialized proteins are required for the maintenance of telomere structure and function. Activation of telomere length maintenance mechanisms is considered a hallmark of cancer, while attrition of...
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