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Article

The three-dimensional organization of telomeres in the nucleus of mammalian cells

3 Jun 2004

Abstract excerpt

BACKGROUND: The observation of multiple genetic markers in situ by optical microscopy and their relevance to the study of three-dimensional (3D) chromosomal organization in the nucleus have been greatly developed in the last decade. These methods are important in cancer research because cancer is characterized by multiple alterations that affect the modulation of gene expression and the stability of the genome....

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Share to Genomic variations and chromosomal abnormalities
Share to Genomics and Chromatin Dynamics
Share to Telomeres, Telomerase, and Senescence

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Identifiers

PMID: 15176976
DOI: 10.1186/1741-7007-2-12

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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