Article
The significance of telomeric aggregates in the interphase nuclei of tumor cells
11 Jan 2006
Abstract excerpt
Telomeres are TTAGGG repetitive motifs found at the ends of vertebrate chromosomes. In humans, telomeres are protected by shelterin, a complex of six proteins (de Lange [2005] Genes Dev. 19: 2100-2110). Since (Müller [1938] Collecting Net. 13: 181-198; McClintock [1941] Genetics 26: 234-282), their function in maintaining chromosome stability has been intensively studied. This interest, especially in cancer...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
