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Close Ties between the Nuclear Envelope and Mammalian Telomeres: Give Me Shelter

23 Mar 2023

Abstract excerpt

The nuclear envelope (NE) in eukaryotic cells is essential to provide a protective compartment for the genome. Beside its role in connecting the nucleus with the cytoplasm, the NE has numerous important functions including chromatin organization, DNA replication and repair. NE alterations have been linked to different human diseases, such as laminopathies, and are a hallmark of cancer cells. Telomeres, the ends...

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PMID: 37107534
DOI: 10.3390/genes14040775

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