Article
Extracellular Microfibrils in Vertebrate Development and Disease Processes
3 Feb 2009
Abstract excerpt
Fibrillins are large cysteine-rich glycoproteins that are evolutionarily conserved from scyphozoans to mammals. Fibrillin assemblies (microfibrils) serve two key physiological functions: the function of a structural support that imparts tissue integrity and the function of a regulator of signaling events that instruct cellular performance (1, 2). The importance of microfibrils in organ formation and tissue...
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