Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fibrillin microfibrils in bone physiology.

Matrix biology : journal of the International Society for Matrix Biology - 1 Jan 2000

Smaldone Silvia, Ramirez Francesco

Abstract excerpt

The severe skeletal abnormalities associated with Marfan syndrome (MFS) and congenital contractural arachnodactyly (CCA) underscore the notion that fibrillin assemblies (microfibrils and elastic fibers) play a critical role in bone formation and function in spite of representing a low abundance component of skeletal matrices. Studies of MFS and CCA mice have correlated the skeletal phenotypes of these mutant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mesenchymal Stem Cells
Share to Osteogenesis
Share to Marfan Syndrome

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Body Patterning

Share to Cell Differentiation

Share to Contracture

Share to Fibrillin-1

Share to Transforming Growth Factor beta

Source

Open in PubMed Open full text

Identifiers

PMID: 26408953
DOI: 10.1016/j.matbio.2015.09.004
PMCID: PMC4808491

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fibrillin microfibrils in bone physiology.PMID 26408953Read ↗

Fibrillin‐rich microfibrils: Structural determinants of morphogenetic and homeostatic eventsSemantic proximity Read ↗

Marfan syndrome; A connective tissue disease at the crossroads of mechanotransduction, TGFβ signaling and cell stemness.Semantic proximity Read ↗

Fibrillin assemblies: extracellular determinants of tissue formation and fibrosisSemantic proximity Read ↗

The fibrillin microfibril scaffold: A niche for growth factors and mechanosensation?Semantic proximity Read ↗

The Multiple Functions of Fibrillin-1 Microfibrils in Organismal Physiology.Semantic proximity Read ↗

New insights into the structure, assembly and biological roles of 10-12 nm connective tissue microfibrils from fibrillin-1 studies.Semantic proximity Read ↗

Extracellular Microfibrils in Vertebrate Development and Disease ProcessesSemantic proximity Read ↗

Biogenesis and function of fibrillin assemblies.Semantic proximity Read ↗

Fibrillin microfibrils: connective tissue pathways that regulate shape and signaling.Semantic proximity Read ↗

Extracellular microfibrils control osteoblast-supported osteoclastogenesis by restricting TGF{beta} stimulation of RANKL production.Semantic proximity Read ↗

Structure and function of the mammalian fibrillin gene family: implications for human connective tissue diseases.Semantic proximity Read ↗

Microenvironmental Regulation by Fibrillin-1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.