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Article

Fibrillin assemblies: extracellular determinants of tissue formation and fibrosis

1 Dec 2010

Abstract excerpt

The extracellular matrix (ECM) plays a key role in tissue formation, homeostasis and repair, mutations in ECM components have catastrophic consequences for organ function and therefore, for the fitness and survival of the organism. Collagen, fibrillin and elastin polymers represent the architectural scaffolds that impart specific mechanic properties to tissues and organs. Fibrillin assemblies (microfibrils) have...

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PMID: 21126338
DOI: 10.1186/1755-1536-3-24

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