Article
Inherited genetic markers discovered to date are able to identify a significant number of men at considerably elevated risk for prostate cancer.
The Prostate - 1 Mar 2011
Sun Jielin, Kader A Karim, Hsu Fang-Chi, Kim Seong-Tae, Zhu Yi, Turner Aubrey R, Jin Tao, Zhang Zheng, Adolfsson Jan, Wiklund Fredrik, Zheng S Lilly, Isaacs William B, Grönberg Henrik, Xu Jianfeng
Abstract excerpt
BACKGROUND: Prostate cancer (PCa) risk-associated single-nucleotide polymorphisms (SNPs) are continuously being discovered. Their ability to identify men at high risk and the impact of increasing numbers of SNPs on predictive performance are not well understood. METHODS: Absolute risk for PCa was estimated in a population-based case-control study in Sweden (2,899 cases and 1,722 controls) using family history and...
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