Article
Common polymorphisms in interleukin genes (IL4, IL6, IL8 and IL12) are not associated with alcoholic liver disease or alcoholism in Spanish men.
Cytokine - 1 Mar 2009
Marcos Miguel, Pastor Isabel, González-Sarmiento Rogelio, Laso Francisco-Javier
Abstract excerpt
BACKGROUND: Preliminary data suggest that polymorphisms in cytokine genes may be involved in the genetic predisposition to alcoholic liver cirrhosis or alcohol use disorders. We thus analyze the association between these diseases and the following polymorphisms: -33T>C IL4, -174 G>C IL6, -251 T>A IL8 and 1188 A>C IL12B. METHODS: 258 male alcoholics (161 without liver disease and 97 with liver cirrhosis) and 101...
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