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Article

Associations of 25 structural, degradative, and inflammatory candidate genes with lumbar disc desiccation, bulging, and height narrowing.

Arthritis and rheumatism - 1 Feb 2009

Videman Tapio, Saarela Janna, Kaprio Jaakko, Näkki Annu, Levälahti Esko, Gill Kevin, Peltonen Leena, Battié Michele C

Abstract excerpt

OBJECTIVE: To examine the allelic diversity of structural, inflammatory, and matrix-modifying gene candidates and their association with disc degeneration. METHODS: Subjects were 588 men ages 35-70 years. We investigated associations of single-nucleotide polymorphisms in AGC1 and in 12 collagen, 8 interleukin, and 4 matrix metalloproteinase genes with quantitative magnetic resonance imaging measurements of disc...

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Identifiers

PMID: 19180518
DOI: 10.1002/art.24268

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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