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Article

Two subtypes of intervertebral disc degeneration distinguished by large-scale population-based study.

The spine journal : official journal of the North American Spine Society - 1 Sept 2016

Li Yan, Samartzis Dino, Campbell Desmond D, Cherny Stacey S, Cheung Kenneth M C, Luk Keith D K, Karppinen Jaro, Song Youqiang, Cheah Kathryn S, Chan Danny, Sham Pak C

Abstract excerpt

BACKGROUND CONTEXT: Lumbar disc degeneration (LDD) is a major cause of low back pain, and is a common and disabling condition worldwide. It has been defined and measured by multiple spine magnetic resonance imaging (MRI) features, but the heterogeneity among them has never been fully addressed. PURPOSE: This study examined the intercorrelations, risk factor associations, and single nucleotide polymorphism (SNP)...

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Identifiers

PMID: 27157501
DOI: 10.1016/j.spinee.2016.04.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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