Phenotype variations affect genetic association studies of degenerative disc disease: conclusions of analysis of genetic association of 58 single nucleotide polymorphisms with highly specific phenotypes for disc degeneration in 332 subjects.

doi:10.1016/j.spinee.2013.05.019

Article

Phenotype variations affect genetic association studies of degenerative disc disease: conclusions of analysis of genetic association of 58 single nucleotide polymorphisms with highly specific phenotypes for disc degeneration in 332 subjects.

The spine journal : official journal of the North American Spine Society - 1 Oct 2013

Rajasekaran S, Kanna Rishi Mugesh, Senthil Natesan, Raveendran Muthuraja, Cheung Kenneth M C, Chan Danny, Subramaniam Sakthikanal, Shetty Ajoy Prasad

Abstract excerpt

BACKGROUND CONTEXT: Although the influence of genetics on the process of disc degeneration is well recognized, in recently published studies, there is a wide variation in the race and selection criteria for such study populations. More importantly, the radiographic features of disc degeneration t...

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Phenotype variations affect genetic association studies of degenerative disc disease: conclusions of analysis of genetic association of 58 single nucleotide polymorphisms with highly specific phenotypes for disc degeneration in 332 subjects.

Abstract excerpt

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