Article
Prolonged use of tenofovir in HIV/hepatitis B virus (HBV)-coinfected individuals does not lead to HBV polymerase mutations and is associated with persistence of lamivudine HBV polymerase mutations.
HIV medicine - 1 Apr 2009
Audsley J, Arrifin N, Yuen L K W, Ayres A, Crowe S M, Bartholomeusz A, Locarnini S A, Mijch A, Lewin S R, Sasadeusz J
Abstract excerpt
OBJECTIVES: The aim of the study was to identify and characterize hepatitis B virus (HBV) polymerase gene mutations associated with ongoing HBV replication in HIV/HBV-coinfected individuals receiving tenofovir (TDF). METHODS: This retrospective cross-sectional study identified 28 HIV/HBV-coinfect...
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