Article
Characteristics of drug resistant HBV in an international collaborative study of HIV-HBV-infected individuals on extended lamivudine therapy.
AIDS (London, England) - 4 Apr 2006
Matthews Gail V, Bartholomeusz Angeline, Locarnini Stephen, Ayres Anna, Sasaduesz Joe, Seaberg Eric, Cooper David A, Lewin Sharon, Dore Gregory J, Thio Chloe L
Abstract excerpt
BACKGROUND: Little is known about the prevalence and pattern of hepatitis B virus (HBV) mutations in HIV/HBV co-infected individuals on long-term lamivudine (3TC) therapy. METHODS: HBV polymerase/envelope/basal core promoter/pre-core sequences from 81 HIV-HBV co-infected persons who received at least 6 months 3TC were compared to HBV reference sequences. Host and viral characteristics associated with HBV...
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