Article
HBV genotypes and response to tenofovir disoproxil fumarate in HIV/HBV-coinfected persons.
BMC gastroenterology - 8 Jul 2015
Bihl Florian, Martinetti Gladys, Wandeler Gilles, Weber Rainer, Ledergeber Bruno, Calmy Alexandra, Battegay Manuel, Cavassini Matthias, Vernazza Pietro, Caminada Anna-Paola, Rickenbach Martin, Bernasconi Enos
Abstract excerpt
BACKGROUND: Hepatitis B virus (HBV) genotypes can influence treatment outcome in HBV-monoinfected and human immunodeficiency virus (HIV)/HBV-coinfected patients. Tenofovir disoproxil fumarate (TDF) plays a pivotal role in antiretroviral therapy (ART) of HIV/HBV-coinfected patients. The influence of HBV genotypes on the response to antiviral drugs, particularly TDF, is poorly understood. METHODS:...
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