Article

Hepatitis B virus resistance to tenofovir: fact or fiction? A synthesis of the evidence to date

2019-10-18

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Tenofovir (TFV) is a widely used antiviral treatment for chronic hepatitis B virus (HBV) infection. There is a high genetic barrier to the selection of TFV resistance-associated mutations (RAMs), but the distribution and clinical significance of TFV RAMs are not well understood, and the topic remains contentious. We here present assimilated evidence for putative TFV RAMs with...

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Literature Corpus work: ce198d16-057a-56fa-b6c6-b9634efca286
DOI: 10.1101/19009563

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