Article
No detectable resistance to tenofovir disoproxil fumarate after 6 years of therapy in patients with chronic hepatitis B.
Hepatology (Baltimore, Md.) - 1 Feb 2014
Kitrinos Kathryn M, Corsa Amoreena, Liu Yang, Flaherty John, Snow-Lampart Andrea, Marcellin Patrick, Borroto-Esoda Katyna, Miller Michael D
Abstract excerpt
UNLABELLED: One major challenge in the treatment of chronic hepatitis B is to maintain long-term viral suppression without promoting the selection of drug-resistant mutations. We analyzed data from 347 hepatitis B e antigen-negative and 238 hepatitis B e antigen positive patients receiving tenofovir disoproxil fumarate (TDF) in an open-label, longterm extension of two phase 3 studies. To date, resistance analyses...
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